(Newswire.net -- January 27, 2015) Alicante, Alicante -- A new 12-year US research study has revealed that the most frequent problems only arrive when drugs were used to stimulate ovaries, though it does suggest that such problems are rarely fatal. Data revealed indicates that over-stimulated ovaries occurred in 154 out of every 10,000 pregnancy attempts, while rates of other complications were less than 10 per 10,000 attempts. There were a reported 58 deaths during the 2000-11 study, though the study does lack information on their causes. The final results were published in the Journal of the American Medical Association, after researchers had examined federally mandated reports from U.S. fertility clinics.
The reports reveals that deaths included 18 within 12 weeks of starting fertility drugs, suggesting the drugs might have played a role, with the other 40 deaths occurring later, suggesting pregnancy-related complications may have been the cause, as 18 of these women were carrying twins, triplets or more. Rates for overstimulated ovaries didn't change during the study, but rates for other medicine side effects and hospitalizations did decline. More stable rates were seen in the report for other problems, including infections, bleeding and anaesthesia complications, while complications were most rare in donors, who were typically healthy young women, and none died, while no data was revealed about the final IVF success rates.
According to experts from IVF-Spain, there are several factors that can lead to in vitro fertilization (IVF) failure, who say that while not all issues related to the failure of IVF can be corrected, some issues can be addressed in an effort to reduce the likelihood of failure during a new cycle. The Spanish fertility clinic say that it is important to understand what factors are involved in each particular situation, with age being a very important factor in the success or failure of IVF. A spokesperson for IVF-Spain explained that as women get older, the number of eggs in the ovaries and the quality of those decreases, with the decline starting at age 30 and increasing quickly after age 37. Statistically speaking they say that the probability of a live birth after IVF with own eggs is about 32% of a 35 year old woman, but only 16% for a 40 old one.
IVF-Spain has stated on their website that in general, the more oocytes that are produced in an IVF Cycle, the more probability there is for success with the cycle. Their official spokesman also said.... "The ovaries of some women do not develop many follicles as they do not respond to medication used for IVF cycles to encourage the ovaries to produce multiple eggs. Patients are likely to respond poorly to IVF medication if they are over 37, if they have high levels of FSH, or a reduced number of eggs are left in the ovaries, with IVF being more likely to fail if less than three mature follicles are produced. A pregnancy loss or miscarriage after IVF may be due to problems with the uterus, such as polyps or fibroids, however many fertility specialists believe that most implantation failures are due to the arrest of the embryo, like the embryo stops growing, which may be the result of a genetic defect that interferes in embryonic development."
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