Research Reveals How Supercomputers Outwit Antibiotic Resistance

(Newswire.net — June 6, 2022) Orlando, FL — Antibiotic resistance is considered to be a growing global health threat. This is why more and more experts are looking into remedies potentially helpful in reducing its prevalence.

A new study has shown that supercomputing may be helpful in keeping pace with the stunning ability of diseases to evolve. This is considered to be a giant leap by scientists in battling the biggest threat to human health. 

This research was carried out by an international team spearheaded by Dr. Gerhard Koenig from the University of Portsmouth. 

It looked into the problem of antibiotic resistance by redesigning existing antibiotics for the purpose of overcoming bacterial resistance mechanisms.  

It is worth noting that antibiotic resistance is found to claim the lives of around 700,000 people every year. This number, according to experts, is expected to rise to millions. It is important to be warned that in the absence of effective antibiotics, there would potentially be a life expectancy decline by 20 years. 

The findings of this interesting study were published in PNAS. 

For decades, computers have been utilized in drug design. However, this study is the first to use a 

multi-pronged computer-guided strategy in making a new antibiotic from an existing one that bacteria have outwitted.

“Antibiotics are one of the pillars of modern medicine and antibiotic resistance is one of the biggest threats to human health. There’s an urgent need to develop new ways of fighting ever-evolving bacteria,” Dr. Koenig, a computational chemist and first author of the paper, said.

“Developing a new antibiotic usually involves finding a new target that is essential for the survival of a wide range of different bacteria. This is extremely difficult, and only very few new classes of antibiotics have been developed in recent times.”

It is vital to resort to the measures found to be particularly helpful in reducing the risk of antibiotic resistance. 

Eliminating the need for antibiotics is vital, and this means reducing the risk of UTIs is vital. This is because antibiotics are considered to be the primary treatment for the infection.  

There are plant-based remedies like D-mannose found to be helpful in warding off the infection. It is worth noting that this therapeutic ingredient has long been studied due to its strong medicinal benefits.  

Today, it is widely obtained through the use of formulas like Divine Bounty D-mannose. Aside from containing superior-quality D-mannose, it also has added cranberry and dandelion extracts (https://www.amazon.com/D-Mannose-600mg-Cranberry-Dandelion-Extract/dp/B01LX5KGF0).