Researchers Highlight Glowing Weapon Against Antibiotic Resistance

(Newswire.net — November 17, 2022) Orlando, FL — The Centers for Disease Control and Prevention warns that every year, about 2.8 million individuals in the United States are infected by antibiotic-resistant bacteria. 

This alarming global health issue continues to claim more lives, particularly killing more than 35,000 Americans every year. 

A research team spearheaded by scientists at The University of Texas at Austin carried out a study.

It involved developing chemical probes that work in identifying a particular enzyme that is produced by some types of E. coli and pneumococcal bacteria. It is worth noting that such an enzyme is known to break down several common types of antibiotics.

This means bacteria end up being dangerously resistant to treatment.

“In response to antibiotic treatment, bacteria have evolved various mechanisms to resist that treatment, and one of those is to make enzymes that basically chew up the antibiotics before they can do their job,” said Emily Que.

Que is an assistant professor of chemistry and one of the leading researchers on the team. 

“The type of tool we developed gives us critical information that could keep us one step ahead of deadly bacteria.”

The findings of this research were published in the Journal of the American Chemical Society.

The investigators zeroed in on the threat shown by the bacterial enzyme called New Delhi Metallo-beta-lactamase (NDM).  They set out to produce a molecule that glows the moment it gets in contact with the NDM enzyme.

It is interesting to learn that when the chemical probes are added to a test tube, they end up binding to the enzyme and glowing. The investigators said that such a tool could actually be useful in alerting healthcare providers to what kind of bacterial threat is impacting their patients and telling them which antibiotics to use.

“The evolution of this bacteria since its discovery in 2008 indicates that not only is it developing antibiotic resistance, it’s attempting to combat this natural human immune process. That’s particularly scary,” Que said.

Scientists are increasingly carrying out studies in an effort to reduce the rates of antibiotic resistance, which is driven largely by antibiotic overuse. To reduce the need for antibiotics, it is wise to combat UTIs through the use of all-natural infection-fighting sugar called D-mannose. 

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This provides a safety net for consumers in case they are unhappy with their purchase, they can have a refund. Pretty much everything that health-conscious and budget-wise consumers look for can be found in this formula.  (https://www.amazon.com/D-Mannose-600mg-Cranberry-Dandelion-Extract/dp/B01LX5KGF0)