A New Research Suggests the Stomach May Be a Key to Battling Obesity

(Newswire.net — February 25, 2022) Orlando, FL — Over the years, Scientists have been carrying out research studies to look into the impacts of some measures against obesity. Experts have long been warning against this condition as it could trigger the onset of certain diseases.

A study was carried out and published in the Scientific Reports.

In this research, it has been found that the stomach may be the secret in battling obesity. The investigators believe that there is a stomach-specific protein that plays a major role in the progression of obesity. 

This research was co-authored by an Indiana University School of Medicine researcher.

The co-author said that the findings could aid in the development of therapeutics helpful for individuals who are struggling to achieve and maintain weight loss. 

The scientists focused on a certain protein called Gastrokine-1 (GKN1), which is produced exclusively and abundantly in the stomach.

It is worth noting that in previous research, it has been found that GKN1 is resistant to digestion and it doesn’t just pass into the intestine but also interacts with the gut microbes. In this research, the findings have shown that inhibiting GKN1 produced significant differences in weight and body fat levels in comparison to when the protein was expressed.

“While diet and exercise are critical to maintaining a healthy weight, some individuals struggle with weight loss — even in cases of bariatric surgery, maintaining weight loss can be a challenge,” said David Boone, Ph.D.

Boone is an associate professor of microbiology and immunology at IU School of Medicine, an adjunct professor in the Department of Biology at the University of Notre Dame, and a co-author of the study. 

“These results are an example of how a better understanding of the gut microbiome and the physiological aspects of obesity — how our bodies regulate metabolism and accumulate body fat — could help inform new therapies,” he added. 

The Centers for Disease Control and Prevention reveals that adult obesity rates have skyrocketed to 42.4 percent in the United States. 

It is important to note that obesity increases not just the risk of diseases like diabetes and stroke, but also the odds of severe illness from Covid-19.

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