Recent Research Now Reveals How to Boost Ability in Fighting UTIs

(Newswire.net — April 8, 2019) Orlando, FL — Antibiotics are medications typically used to fight urinary tract infections. However, not many people are aware that there are pharmaceutical drugs potentially helpful in fighting this infection.

Scientists from the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences conducted a study. They found that an experimental drug has an ability to stabilize HIF-1alpha. This protein offers protection to human bladder cells and mice from a major UTI pathogen.

This research was published by PLOS Pathogens. The investigators suggest it could provide a complement to standard antibiotic treatment. According to researchers, the HIF-1alpha can influence the innate immune response, which is the first line of defense in the body against intruding pathogens. It is like many regular proteins that is relatively short-lived.

In increasing the HIF-1alpha levels, the scientists came up with drugs that delay its breakdown. The similar pathway has actually been the target for medications now in advanced clinical trials for anemia treatment.

Victor Nizet, MD, professor of pediatrics and pharmacy, and colleagues tried to see how the HIF-1alpha-stabilizing drugs can boost the innate immune response to uropathogenic E.coli bacteria.

It is worth mentioning that the E.coli bacteria is a major cause of UTIs. It was found that in healthy human urinary tract cells. Medications increased the levels of HIF-1alpha levels.

They also found that the cells ended up more resistant to UPEC attachment, killing, and invasion compared to urinary tract cells that have normal HIF-1alpha levels.

More studies are still underway to validate this research. Today, health care providers strongly recommend taking the measures necessary to prevent the onset of this infection. While antibiotics are helpful, it is hard to deny they also cause some side effects.

Some safer alternatives like D-mannose have been recommended for UTIs. This powerful sugar is believed to be the helpful not just in the prevention, but also the treatment of the infection.

Scientists found that it sticks with the E.coli bacteria that cause infection. Doing this may be significantly helpful in preventing and treating UTIs. There are many who use cranberry juice, but it is wise to consume D-mannose through supplementation.

Divine Bounty D-mannose is one of the formulas in the market that gains more and more attention from consumers. It is thought to be effective in helping those with this infection.

It can also be useful in maintaining an infection-free urinary tract. It is highly potent and is crafted carefully in an FDA-inspected facility in the United States (www.amazon.com/D-Mannose-600mg-Cranberry-Dandelion-Extract/dp/B01LX5KGF0).