A Study Shows E.coli Can Cause the Worst Possible Infection

(Newswire.net — May 2, 2022) Orlando, FL — Scientists have long been warning against the E.coli bacteria, which account for around 90 percent of all UTI cases.

Researchers from the University of Virginia School of Medicine have shown that E.coli targets the most oxygen-free crevices of the colon for the purpose of causing the worst infection possible.  

Such a discovery could one day let doctors prevent the infection by allowing E.coli to pass through the body harmlessly. It shows how the foodborne pathogen identifies the spot and time to start colonizing the colon on its way to making the body sick.  

Through the ability to recognize the low-oxygen environment of the large intestine, these dangerous bacteria provide the best odds of establishing a robust infection. It is worth noting that this is one that is punishing for the host. 

“Bacterial pathogens typically colonize a specific tissue in the host. Therefore, as part of their infection strategies, bacterial pathogens precisely time the deployment of proteins and toxins to these specific colonization niches in the human host. This allows the pathogens to save energy and avoid detection by our immune systems and ultimately cause disease,” said researcher Melissa Kendall, Ph.D.

Kendall is from UVA’s Department of Microbiology, Immunology, and Cancer Biology. 

“By knowing how bacterial pathogens sense where they are in the body, we may one day be able to prevent E. coli, as well as other pathogens, from knowing where it is inside a human host and allow it to pass through the body without causing an infection.”

Through this study, Kendall and graduate student Elizabeth M. Melson were able to shed important light on how harmful E.coli infections are able to establish themselves in the body. 

“If scientists can figure how to block oxygen sensing, we may be able to prevent E. coli from making proteins that allow it to stick to our guts,” Kendall said. “This may be an effective strategy to limit infection, and because we are not targeting growth or survival, E. coli may not develop drug resistance — it just doesn’t know where it is.” 

In fighting UTIs in a natural way, it may be wise to use a therapeutic sugar called D-mannose.

Divine Bounty D-mannose is a highly recommended formula today. There are many features that make this supplement superior to other brands. 

Aside from having 600 mg of superior-quality and potent D-mannose, it also has cranberry and dandelion extracts. It continues to receive positive reviews from health-conscious and budget-wise consumers (https://www.amazon.com/D-Mannose-600mg-Cranberry-Dandelion-Extract/dp/B01LX5KGF0).