Researchers Now Found Genetic Incompatibility Underlies Many Kidney Transplant Failures

(Newswire.net — July 6, 2022) Orlando, FL — Due to the increasing prevalence of kidney disease, more and more studies look into the various aspects of kidney health.

A study was carried out and published in the New England Journal of Medicine. 

It was carried out by the researchers at Columbia University Vagelos College of Physicians and Surgeons.

It has been found that the potential culprit of a number of kidney transplant failures may be a genomic collision. This stays true even when donors and recipients are thought to be well-matched.

It is important to note that genomic collision pertains to genetic incompatibility between a kidney donor and recipient. This causes the recipient to mount an immune attack against the donor protein.

The findings of this research could result in a reduction in kidney transplant failures as well as a more precise matching between donors and patients. Experts also reveal that the same genomic collision may also potentially occur in heart, liver, and lung transplants.

According to co-senior author Krzysztof Kiryluk, MD, the rest of those failures are probably due to less common antigens, or so-called minor histocompatibility antigens.

Kiryluk is the Herbert Irving Assistant Professor of Medicine at Columbia University Vagelos College of Physicians of Surgeons.

“However, the identity of most of these antigens and how they lead to rejection is largely not known,” Kiryluk adds.

The National Kidney Foundation (NKF) has been leading the way in rallying action against chronic kidney disease. 

In the United States, it has been found that 15 percent of the adult population has chronic kidney disease (CKD). It is also worth mentioning that 90 percent of those who have this condition do not know they have it. 

Still in the U.S., roughly 80 million people are found to be at a heightened risk of CKD. It is actually more common in women by 15 percent than in men, which has a prevalence rate of 12 percent. 

As the rates of kidney health issues continue to soar, more and more studies look into the effects of using some natural remedies like magnesium to combat them.

A study was published in the American Journal of Nephrology.

In this research, the investigators found a correlation between low dietary magnesium intake and kidney function decline.

This is just one of the studies demonstrating the value of magnesium in taking care of the kidneys. It is also worth mentioning that aside from its kidney health benefits, magnesium is also thought to combat a range of diseases.

Experts strongly recommend ensuring adequate intake of this macromineral. There are reliable and effective sources like Divine Bounty Magnesium Citrate consumers may take into account using (www.amazon.com/Divine-Bounty-Magnesium-Citrate-Supplement/dp/B01LYWPNY6).