Research Highlights a Potential Strategy in Battling Obesity

(Newswire.net — October 14, 2022) Orlando, FL — Years of research have strengthened the warning against obesity, which has long been associated with the increased risk of diseases.

A study carried out by UT Southwestern scientists have identified a technique for safely mimicking the weight-loss benefits of Celastrol, which is derived from the root extracts of a white-flowered plant in China.  

It is worth noting that this plant compound may offer a vital solution in the development of therapies for obesity. 

In recent years, celastrol has caught the attention of scientists due to its remarkable potential in preventing and reversing obesity in mice. However, it has been found to cause reactions like lethargy and hypertension in mouse subjects.

This is why researchers tried to see how this compound works and how it can be used as a safe weight-loss treatment in humans. 

In this research, UT Southwestern has found that celastrol needs a specific protein in a type of neuron, which influences metabolism. They were able to mimic a “fed” signal to the brains of the mouse subjects by deleting such a protein from the neurons.

Interestingly, it led to mice losing 7 percent of their body weight in just two weeks despite having a high-fat diet. One key finding is that the subjects did not seem to suffer from the same physical ailments recorded in previous research, in which celastrol was used.  

“This new understanding of how celastrol works on the cellular level open more possibilities for targeting pathways that can improve our metabolism without the negative health impact,” said study author Kevin W. Williams, Ph.D.

Williams is an investigator at UT Southwestern’s Center for Hypothalamic Research.

“We haven’t uncovered all the cell populations that influence weight loss, but each of these findings brings us closer to developing effective, safe therapies for obesity.”

The findings of this research were published in JCI Insight. More studies are still being carried out to look into the remedies helpful in managing a healthy weight. It is worth keeping in mind that many of the most common and deadly diseases are preventable through weight management.

It is vital to make dietary and lifestyle improvements, as well as use some weight-control supplements like Divine Bounty L-Carnitine.

This therapeutic remedy has long been studied due to its remarkable healing benefits. It’s been found to enhance levels of energy, which is vital for exercise adherence and optimum performance.

It is worth noting that this remedy can also work wonders in helping the body shed extra pounds. Divine Bounty L-Carnitine may also deliver the remarkable healing benefits the use of this amino acid is linked with (amazon.com/dp/B06XF7K9MM).