Scientists Now Reveal How Multi-Drug Resistant Bacteria Can Emerge

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( — December 1, 2022) Orlando, FL — Today, health authorities are strongly warning against antibiotic resistance and its dangerous health effects. 

The Centers for Disease Control and Prevention warns that annually, antibiotic-resistant bacteria affect some 2.8 million Americans. It is further worth noting that in the country, it takes the lives of more than 35,000 individuals. 

Scientists at the University of Washington and the University of Idaho carried out a study and revealed just how readily MDR bacteria can emerge. 

The findings of this interesting study were published in Nature Ecology & Evolution.

The researchers revealed that for a bacterial pathogen already resistant to an antibiotic, prolonged exposure to that antibiotic not only increased its ability to retain its resistance gene but also trigged the pathogen to be more readily picked up. 

Further, the pathogen also ended up maintaining resistance to a second antibiotic and becoming an MDR strain.

The experiments of the research team indicate that prolonged exposure to one type of antibiotic “primed” the bacteria essentially. It is important to mention that the priming effect actually increased the likelihood of the bacteria acquiring resistance to additional antibiotics. 

This stays true even without further antibiotic exposure. Such priming effect also helped the strain hold on to those antibiotic-resistance traits for generations.

“Exposure to antibiotics appears to select indirectly for more stable antibiotic resistance systems,” said Benjamin Kerr, a UW professor of biology and co-senior author of the paper. 

“A more stable system in a strain will increase the chances that it will acquire resistance to multiple antibiotics.”

According to Eva Top, this could help explain not only the rise of multi-drug resistance in bacteria but also how antibiotic resistance persists and spreads in the environment — in healthcare settings, in soil from agricultural runoff — even long after the antibiotic exposure has ended.

Eva Top is a co-senior author and a professor of biology at the University of Idaho.

Scientists have been introducing some remedies potentially useful against antibiotic resistance. One of the techniques involves the use of D-mannose, which helps combat UTIs. It is worth noting that UTIs drive the increase in antibiotic use and overuse.

The proven health benefits of using this remedy may be obtained through the use of superior-strength supplements like Divine Bounty D-mannose. 

Before reaching the market, the company ensures that every product is crafted carefully in an FDA-inspected facility in the U.S. according to Good Manufacturing Practices (GMP) guidelines and strict regulations. 


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