More Evidence Highlights Effects of Cranberry on UTI Prevention

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( — December 26, 2022) Orlando, FL — Today, more and more researchers are looking into the all-natural remedies helpful against UTIs. It is worth noting that this type of infection is often treated with pharmaceutical drugs like antibiotics. 

A study reveals that the chemicals found in cranberries have the ability to inhibit infection-causing bacteria from latching on to the cells lining the urinary tract.

The findings of this interesting research were published in the Journal of Medicinal Food. 

It is important to be warned that UTIs cause a burden to the healthcare system, leading to over $2 billion in treatment costs each year. It is actually a common problem in patients with a urinary catheter in place. 

According to experts, the first step in the development of the infection is the adhesion of E. coli bacteria to cells lining the urinary tract.

The researchers revealed that certain chemicals present in cranberry called proanthocyanidins (PACs) prevent E. coli adhesion to the urinary tract epithelial cells. These chemicals particularly work by affecting the surface properties of E.coli, which is the cause of about 85 percent of UTIs and 90 percent of cases of acute pyelonephritis.

In this research, Paola Pinzón-Arango, Yatao Liu, and Terri Camesano, from Worcester Polytechnic Institute, in Massachusetts, exposed the bacteria to either a light cranberry juice cocktail or cranberry PACs.

It has been found that longer exposure of bacteria to either cranberry juice or the PACS leads to a greater reduction in bacterial attachment. 

“Cranberries, one of only three species of fruits native to North America, has a long history of medicinal food use. Native Americans used the fruit for the treatment of bladder and kidney ailments hundreds of years ago. The article by Camesano and co-workers is a milestone in the understanding of its mechanism of action,” says Sheldon S. Hendler, Ph.D., MD.

Hendler is Co-Editor-in-Chief of the Journal, and Clinical Professor of Medicine, at the University of California, San Diego. 

Another widely studied-on ingredient in cranberry is D-mannose, which is a therapeutic sugar being used in the prevention and treatment of infection.

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