(Newswire.net — January 16, 2023) Orlando, FL — Today, scientists are increasingly investigating the remedies helpful in the management of osteoarthritis. There are even certain medications intended for other conditions that are used for arthritis symptoms.
A review has shown that antidepressant drugs are largely ineffective for back and osteoarthritis pain. It is worth noting that these medications are being widely used for these conditions.
The findings of this interesting research were published in The BMJ.
The researchers have particularly revealed that for individuals with back pain, the impacts were too minimal to be worthwhile. However, for osteoarthritis, a small beneficial impact cannot be ruled out.
It is worth noting that a majority of clinical practice guidelines recommend the use of antidepressants for long-term chronic back pain and osteoarthritis in the knee and hip.
Scientists carried out this research being spearheaded by Giovanni Ferreira at the University of Sydney. The investigators tried to see the effectiveness and safety of antidepressants for back and osteoarthritis pain compared with a placebo.
The findings are based on an analysis of published data taken from 33 randomized controlled trials that involved more than 5,000 adults with low back or neck pain, sciatica, or hip or knee osteoarthritis.
Results revealed that serotonin-norepinephrine reuptake inhibitors (SNRIs) lessened back pain after three months. However, the effect was small, with an average difference of 5.3 points on the pain scale compared with a placebo.
“Large, definitive randomized trials that are free of industry ties are urgently needed to resolve uncertainties about the efficacy of antidepressants for sciatica and osteoarthritis highlighted by this review.”
Today, there are increasingly popular remedies for pain relief and arthritis that researchers are investigating. One is glucosamine, which is popularized by its cartilage-repairing benefits. There are many arthritis sufferers who turn to its use as a safer alternative to pain relievers.
This amino sugar has further been found to produce other health benefits.
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