Research Reveals an Aging Skin Loses Ability to Form Fat

(Newswire.net — April 19, 2022) Orlando, FL — Various research studies have highlighted the impacts of aging on the skin. One study has particularly shown that during aging, its ability to form fat may wane or be lost. 

According to researchers, there are specialized cells deep in the skin called dermal fibroblasts that generate connective tissue and aid in skin recovery during an injury. 

It is worth noting that some fibroblasts actually have the ability to convert into fat cells residing under the dermis. This gives the skin a youthful, plump look and produces a peptide that plays a vital role in battling infections. 

This study carried out by University of California San Diego School of Medicine researchers was published in Immunity.

The investigators have demonstrated how fibroblasts develop into fat cells and identified a certain pathway that triggers the process to cease as people age.

“We have discovered how the skin loses the ability to form fat during aging,” said Richard Gallo, MD, Ph.D., Distinguished Professor and chair of the Department of Dermatology at UC San Diego School of Medicine and senior author of the study. 

“Loss of the ability of fibroblasts to convert into fat affects how the skin fights infections and will influence how the skin looks during aging.”

It is also important to note that gaining weight will not help convert dermal fibroblasts into fat cells. This is due to the fact that obesity also interferes with the body’s ability to combat infections.

What happens is that a certain protein halts dermal fibroblasts from converting into fat cells. This protein is called transforming growth factor-beta (TGF-β), which controls a number of cellular functions. 

What makes this protein even more intriguing is that it works in preventing cells from producing the antimicrobial peptide cathelicidin, which aids in the protection against bacterial infections.

More studies are still underway to look into the various aspects of skin health and aging. Time and again researchers recommend making dietary and lifestyle improvements in protecting and enhancing skin health.

These measures are also useful in delaying the signs of aging. Interestingly, some studies have shown that a medicinal mushroom called lion’s mane produces skin health benefits.

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Today, it is widely reported through the use of supplements like Divine Bounty Lion’s Mane. This amazing formula is known for its high potency and purity, and it even comes with a customer satisfaction guarantee. (amazon.com/Organic-Lions-Mane-Mushroom-Capsules/dp/B07LGR1KN7).