A Study Found Bacterial Toxin in UTI Patients

(Newswire.net — August 30, 2021) Orlando, FL — Over the years, researchers have been carrying out studies to look into the various aspects of urinary tract infections. UTIs are undeniably common today and are a major cause of the increasing demand for antibiotics.

A study was carried out and published on February 25th in the open-access journal PLOS Pathogens.

It was carried out by Jean-Philippe Nougayrède and Eric Oswald of Université de Toulouse, and colleagues.

This research has discovered a DNA-damaging bacterial toxin called colibactin in patients with urinary tract infections (UTIs).

Roughly 150 million individuals suffer from UTIs every year. It is most common in women and this is due to the fact that they have a shorter urethra. This type of infection is known for its negative impacts on mortality rates and the economy. 

According to studies, it is the uropathogenic E. coli (UPEC) that causes roughly 80 percent of all UTIs. 

In this research, it has been found that colibactin is produced in individuals with UTIs and infection with UPEC. It is worth noting that colibactin is suspected of being involved in cancer, and the UPEC strains produced colibactin. 

The study involved analysis of urine samples from 223 patients with community-acquired UTIs. The researchers particularly found that colibactin-producing bacteria-induced extensive DNA damage in bladder cells. 

“Our work suggests that there should be a more specific follow-up of patients regularly suffering from urinary tract infections, with a systematic search for colibactin markers in their urine, but also more proactive, by proposing therapeutic approaches aimed at modulating the composition of their intestinal microbiota, which represents the main reservoir of the E. coli bacteria involved in these urinary tract infections,” the authors concluded.

Urinary tract infections (UTIs) are often treated through the use of antibiotics. It is worth keeping in mind that there are also some all-natural remedies like D-mannose found to be particularly useful. 

When ingested, D-mannose binds with the UTI-causing bacteria and eliminates them from the body. Intake of formulas like Divine Bounty D-mannose is extremely popular nowadays, especially among those who are prone to infection.

Divine Bounty D-mannose is known for its high potency and purity. It could be an excellent choice for individuals who don’t want to experience the side effects of antibiotics, which are found to cause antimicrobial resistance. 

It is made carefully in an FDA-inspected facility in the U.S. It continues to be a popular choice among health-conscious and budget-wise consumers (http://www.amazon.com/D-Mannose-600mg-Cranberry-Dandelion-Extract/dp/B01LX5KGF0).