New Research Now Finds Link Between Estrogens and Heart Physiology Changes

(Newswire.net — December 13, 2018) Orlando, FL — More and more clinicians and researchers are investigating on the effects of estrogen, which is a female hormone. In a study, it has been found to affect the heart.

Scientists suggest that certain pollutants found in the environment can mimic estrogens. These are xenoestrogens that they discovered to potentially have deleterious effect on heart function.

The study was performed by University of Alabama at Birmingham Zebrafish Research Facility.

Daniel Gorelick, Ph.D., assistant professor of pharmacology and toxicology at UAB, has produced zebrafish mutants in four different receptors that respond to estrogens.

It is worth mentioning that these four different receptors are found on the surface or inside of cells. The scientists utilized mutants to aid in unraveling a novel mechanism of the action of estrogen on heart physiology.

He suggests that the broader use of the mutants may have important implications for studies focusing on estrogenic environmental endocrine disruptors.

According to researchers, estrogens are powerful hormones essential not just for the formation but also function of the reproductive, nervous, and cardiovascular systems.

Xenoestrogens, on the other hand, are environmental chemicals that mimic estrogens. They may be both industrial pollutants and natural compounds that may also be toxic for human health. Xenoestrogens are known as estrogenic environmental endocrine disruptors.

Experts have long warned that environmental estrogen-mimicking compounds can be harmful. This is due to the fact that they have the ability to influence the gonad function.

The findings of the study suggest that endocrine disrupting compounds may also have an influence in cardiac function.

This study was published in PLOS Genetics.

It can’t be denied that estrogen is essential for good health. Unfortunately, there is a growing threat that xenoestrogens can produce. Xenoestrogens may come from pesticides, plastic bottles, and some other contaminants.

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