Rheumatologists Reveal the Reasons Why Osteoarthritis Is Painful

(Newswire.net — July 5, 2017) Orlando, FL — Pain is a common consequence of having arthritic conditions, such as osteoarthritis. While it is imperative to learn about the best possible treatment options, it is also important to know what causes such a symptom.

Rheumatologists reveal the reasons why osteoarthritis is painful. This chronic arthritic disease is characterized by pain and other debilitating symptoms.

It is worth mentioning that the cartilage is an aneural, avascular tissue, and the mechanism of pain is prone to complexities. It could also be influenced by the joint’s non-cartilaginous structures, which include the bone, synovium, and soft tissue.

In imaging studies, it was found that there is a presence of synovitis as well as bone marrow lesions that may potentially mediate pain.

According to researchers, there is an implication that altered cartilage and bone turnover as well as the presence of local joint inflammation play a possible role for various molecular mediators in pain caused by osteoarthritis.

There are mechanisms of pain perception, and one is the activation as well as the release of certain pro-inflammatory mediators, and this includes cytokines and prostaglandins.

These pro-inflammatory mediators may be accompanied by tissue destruction, which protease mediates.

In a clinical setting, researchers found a disparity between the level of joint changes and the degree of pain perception in study participants with osteoarthritis. These observations have led them to try to determine the mechanisms of central pain perception in osteoarthritis.

In the United States alone, osteoarthritis is the most common arthritic condition. The number of sufferers has also been found to grow among the aging populations. The most common joints affected are the weight-bearing ones, such as the knee, hands, and hip.

According to statistics, this condition affects 50 percent of individuals who are 65 years and above. It can also develop in younger individuals after a joint injury. This figure is expected to rise due to the increasing prevalence of obesity and the aging population.

The condition is characterized by cartilage degradation. It causes pain and disability due to the loss of cartilage. However, it has been estimated that 40 percent of sufferers with radiological damage suffer no pain.

There are supplements, such as glucosamine, that are thought to be helpful in improving joint cartilage health. This natural ingredient is thought to help in repairing cartilage damage, which could be helpful to individuals with osteoarthritis.

Those who want to protect their cartilage health may also turn to glucosamine supplementation.

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