Study Sheds Light on Osteoarthritis Prevalence in Women

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( — September 19, 2018) Orlando, FL — Osteoarthritis can affect people of any age or gender, but it has been found to be more common in women. It has not actually been identified yet what causes the condition, but there are risk factors for its development.

A study has shed light on osteoarthritis prevalence in women. This condition has actually been found to be more common in women in older age than men. In a new study, the researchers tried to identify the differences in the synovial fluid in women and men with the condition. 

This study was co-authored by Dr. Monte Hunter, chair of the Department of Orthopedic Surgery at the Medical College of Georgia at Augusta University, and was published in the Scientific Reports. 

The synovial fluid surrounds the joints and works by protecting the cartilage, which is the tissue that covers the ends of the bones. In cases of osteoarthritis, the cartilage deteriorates and this causes friction while a person moves. 

It is further worth mentioning that the synovial fluid contains information that is useful in determining joint health. The investigators of this study tried to see whether or not there were differences in this information between men and women sufferers of osteoarthritis. 

The researchers got samples of synovial fluid from the knees of participants with and without osteoarthritis. They focused on the exosomes of synovial fluid. It is important to note that these are vesicles in the fluid that carry microRNAs, which are small molecules. These actually work in regulating gene expression. 

In the analysis, it was found that there were significant differences in miRNA activity between women and men with the condition. Further, it was found that the synovial fluid of men had 69 downregulated and 45 upregulated miRNAs. The investigators also found that in women the synovial fluid had 53 upregulated and 91 downregulated miRNAs. 

In women, the microRNA activity has been linked with 70 altered biological processes, and this was compared with approximately 50 altered biological processes among men. It is interesting to learn that women are actually more prone than men in showing an alteration or deactivation of miRNAs, which are essential for estrogen signaling and collagen production. 

To manage osteoarthritis, there are those who turn to the use of pharmaceutical drugs, while others resort to joint health enhancing formulas like glucosamine. This fantastic natural remedy has actually been found helpful due to its ability to repair cartilage damage. 

VitaBreeze Glucosamine formula is an excellent choice. It is equipped with high levels of glucosamine’s anti-arthritis properties. It is not just highly potent and pure, but is also backed with a complete customer satisfaction guarantee.


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