(Newswire.net — April 1, 2022) Orlando, FL — Today, researchers continue to carry out studies investigating the ways to combat dementia. Time and again it has been found some therapeutic compounds in food exhibit therapeutic potentials.
The USC researchers carried out a study and had it published in the Journal of Biological Chemistry.
In involved mouse subjects with Alzheimer’s-like symptoms that were programmed genetically to develop the disease.
It further involved randomly grouping 32 mice into four with an equal number of males and females. The treatments involved were a combination of EGCG and FA, or EGCG or FA only, or a placebo for three months.
The findings have shown that a special diet, which has compounds that can be found in carrots and green tea, helped in restoring working memory. Researchers said that plant-based supplements may offer protection against dementia in humans.
“You don’t have to wait 10 to 12 years for a designer drug to make it to market; you can make these dietary changes today,” said senior author Terrence Town.
Town is a professor of physiology and neuroscience at the Keck School of Medicine of USC’s Zilkha Neurogenetic Institute.
“I find that very encouraging,” he added.
The findings of this research provide addition support to previous studies showing that combination treatment may be better than a single magic bullet. It is worth realizing that combination treatment has long been utilized as the standard of care for diseases like cancer, HIV infection, and rheumatoid arthritis.
In green tea, the researchers looked into its compound called the EGCG, or epigallocatechin-3-gallate. The other compound is called FA, or ferulic acid, which is found in rice, carrots, tomatoes, wheat and oats.
More studies are still underway to look into the therapeutic compounds beneficial for brain health. It is worth noting that some amino acids like L-carnitine are also found helpful.
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