(Newswire.net — September 26, 2022) Orlando, FL — The prevalence of antibiotic resistance continues to cause alarm in the scientific community. Experts have time and again warned that this issue is a growing global health threat.
A computational research at Chalmers University of Technology, Sweden reveals that antibiotic resistance may spread even more easily than expected.
One reason could be the substantial genetic transfer between bacterial in the ecosystems and humans. The findings of this research may pave way for the development of new tools useful for resistance researchers.
The World Health Organization warns that antibiotic resistance is one of the biggest threats to food safety and development as well as global health. In Europe alone, it has already led in more than 33,000 deaths a year.
According to experts, totally different species of bacteria can actually spread resistance genes to each other through plasmids. It is worth noting these are small DNA molecules where bacteria store some of their genes outside the chromosome.
Contact in between two bacterial cells can lead in the plasmids to copy each other, and this occurrence is called conjugation. Experts say it is the most essential mechanism for spreading antibiotic resistance.
“In recent years, we’ve seen that resistance genes spread to human pathogens to a much greater degree than anyone expected,” says Jan Zrimec, researcher in systems and synthetic biology at Chalmers University of Technology.
“Many of the genes appear to have originated in a wide array of bacterial species and environments, such as soil, water and plant bacteria.”
The researcher also said that this has actually been hard to explain, and this is due to the fact that while conjugation is quite common, it has been thought there was a distinct limitation for which bacterial species can transfer plasmids to each other.
Time and again experts say that there are measures potentially helpful in fighting antibiotic resistance. One involves the use of a therapeutic sugar called D-mannose, which binds with UTI-causing bacteria.
It is worth noting that antibiotic overuse or misuse has long been found to fuel the increase of antibiotic resistance rates. By inhibiting the development of UTIs, the need for antibiotics and the risk of overusing it may also be lessened or eliminated.
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